Fellow Blogger David Marusek's debut novel Counting Heads is terrific. I'll not try to top the review Cory Doctorow wrote for Amazon, but I will add my USD$0.02.
Do you remember the feeling you had when you read Neuromancer for the first time? The feeling of abandonment, of being entirely swept away not only by the narrative but by the concept behind the novel?
OK, take that feeling, add characters you can actually sympathize with, and you've got Counting Heads. Everyone except the affs are human, and that's no different than the real world, IMO.
The fact that it takes place in Chicago is a bonus worth noting. Bears.